|
KMID : 0370220090530050298
|
|
Yakhak Hoeji
2009 Volume.53 No. 5 p.298 ~ p.302
|
|
|
The Effects of Mume Fructus Extracts on Blood Flow Improvement
|
|
Park Seung-Hee
Kim Jae-Ki
Park Keum-Ju
|
|
|
Abstract
|
|
|
|
Mume Fructus extract is used in folk medicine in Eastern Asian countries including Korea. However, its therapeutic effect on thrombosis is not known. Mume Fructus methanol extract (ME) dose-dependently inhibited ADP-induced platelet aggregation and also exhibited about 130% fibrinolytic activity compared to the natto. Oral administration of ME to mice significantly extended tail-bleeding time. ME prolonged both aPTT and PT in human citrated plasma also. These results suggest that the methanol extract from Mume Fructus have antithrombosis activity.
|
|
|
KEYWORD
|
|
|
Platelet, Mume Fructus, antithrombosis, fibrinolysis, anticoagulant
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|